Cremophor RH 60 is anon-ionic solubilizer and emulsifying agent obtained by reacting hydrogenated castor oil with ethylene oxide.It conforms to the Ph. Eur. requirements. Used to solubilise ethereal oils, perfume compositions, vitamins and hydrophobic active substances in aqueous- alcoholic and purely aqueous solutions. The finished preparations are particularly stable. Cremophor RH 60shows little tendency to foaming, which is particularly important for solutions in aqueous ethanol. Further foam suppression can be obtained by adding a small amount of defoamer.
The undiluted Cremophor RH 60is white to yellowish soft or flowing pastes at 23 °C and hasthe outstanding feature that its aqueous solutions have a very faint odor.Cremophor RH 60forms nearly clear solutions in water, ethanol and isopropanol, and in essential oils and other hydrophobic compounds, e.g. vitamins and alpha-bisabolol. Can be mixed with other Cremophor grades. With gentle heating, forms clear mixtures with fatty acids and fatty alcohols.