Skin microbiota diversity changes with age: Certain beneficial lactic acid bacteria are reduced; some even disappear from mature skin. BASF researchers now found out that Lactobacillus crispatus is decreasing on certain skin areas, and cannot even be detected in the wrinkle hollow of older persons anymore. BASF makes these live bacteria available as a cosmetic Probiotherapy. Unlike other biotics existing on the cosmetic market, Probiolift uses a bacterium that is found naturally on the skin. Made of millions of live but dormant bacteria, that wake up in contact with water on the skin, Probiolift increases the dermal density, improves the appearance of forehead wrinkles, and protects skin from oxidative stress.

Complementing existing research that indicates skin microbiota diversity changes with age, BASF has conducted a new study on the difference in the facial microbiome composition of wrinkled and non-wrinkled skin. The research team found that lactic acid bacteria, including Lactobacilli, noticeably decrease in mature, wrinkled skin. A particular species, Lactobacillus crispatus, has a pronounced decrease in the undereye and crow’s feet zone and was undetectable within the wrinkle area of older skin. This finding has led BASF researchers to develop 2 technologies based on L. crispatus, isolated from human skin, to help support more youthful looking skin.


Two cosmetic ingredients were developed from the same fermentation process: Probiolift®, the probiotic with dormant cells of living L. crispatus, and Postbiolift®, the fermentation supernatant containing the metabolites secreted by L. crispatus.


Dormant, living cells of the “youth bacterium” Lactobacillus crispatus, a beneficial microorganism naturally occurring on young skin.

Matrix protection
Elasticity & Firming
      • INCI
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        Maltodextrin (and) Lactobacillus