Hydra Synol® DOI is a well-defined compound, lipophilic with excellent skin feel and is completely odorless. It is a smart skin hydrator and barrier builder that intelligently provides optimum hydration based on skin
moisture content/deficit.

Key Features:

• Clinically shown to be very effective in providing long-lasting (>48 hrs.) and controlled skin hydration.
• The beneficial effects on the skin can be explained by the up-regulation of AQP3, CD44 (hyaluronic acid receptor) and tight junction genes, decrease of which is associated with a defective osmotic equilibrium in the epidermis and dryness of chronically and photoaged skin.
• It stimulates ceramide synthase 3, key enzyme responsible for Ceramide boosting.
• DOI has unique anti-inflammatory properties, works by inhibiting TRPA1, TSLP, TRPV3, IL1β and TNFα pathways.

Sytheon limited was purchased in November 2024 and their line of products including this one is now available within the Hallstar Beauty portfolio.